XXVIII. Sweden

Lecture XXVIII: Horizons and the area theorem

We begin by reconsidering the nature of the horizon. As we found in the Schwarzschild case, when properly considered in terms of a set of coordinates that are nonsingular at the horizon (ũ, ṽ, θ, φ), the horizon (in that case, ũ = 0) is actually a 3-dimensional submanifold H of the overall 4D manifold M. This is not surprising since it represents a boundary between the region observable by an o...

EURO Mini Conference (MEC XXVIII) on Variable Neighborhood Search

We are presenting in this volume selected, peer-reviewed, short papers that were presented at the EURO Mini Conference XXVIII on Variable Neighborhood Search (MEC XXVIII VNS) which was held during October 4-7, 2012, in Herceg Novi, Montenegro.

Developments in Practice XXVIII: Managing Perceptions of IS

International Union of Pharmacology. XXVIII. Proteinase-activated receptors.

Proteinase-activated receptors (PARs) represent a unique subclass of G-protein-coupled receptors of which four family members have now been cloned from a number of species. The novel mechanism of receptor activation involves the proteolytic unmasking of a cryptic N-terminal receptor sequence that, remaining tethered, binds to and triggers receptor function. In addition, short (five to six amino...

Genetics of childhood disorders: XXVIII. Autoimmunity, part I.

855 The immune system fights infection by recognizing and destroying invading pathogens. To do this effectively, it must distinguish between proteins that are foreign and those that are not. Once this skill is acquired, the immune system is able to recognize foreign antigens and initiate an immunological response against them while ignoring proteins that are not foreign. Occasionally the immune...